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BumRushDaShow

(160,708 posts)
Sat Sep 27, 2025, 05:45 AM 18 hrs ago

FDA Commissioner Dr. Marty Makary tells Scripps News 'I don't think autism is genetic'

Source: Scripps News

Posted 5:49 PM, Sep 26, 2025 and last updated 1 hour and 49 minutes ago


Dr. Marty Makary, commissioner of the Food and Drug Administration, said he does not believe autism is a genetic condition, calling it instead a “modern-day phenomenon.”

"I don't believe autism is genetic. When you see the severe autism that we see, at the high rate that we see today — the repeated motions, the ticks, the individuals who are completely nonverbal, you didn't see that a generation ago," he said in an interview with Scripps News. "You still don't see people in their 60s and 70s with those symptoms — the sort of repetitive motions, the completely non-verbal individuals."

This week, federal health officials warned of the possible link between Tylenol and its active ingredient, acetaminophen, during pregnancy to autism — despite contested science.

"The number one thing was that we found for some kids, autism is an autoimmune disease, whereby their body is reacting to the folate receptor on the brain, blocking the brain from getting this critical vitamin," Makary said. "There's a treatment called leucovorin that some kids take and have a marked improvement in their autistic symptoms." Makary explained that he and the FDA are now investigating a theory that recent rates of severe autism are not genetic.

Read more: https://www.scrippsnews.com/health/fda-commissioner-dr-marty-makary-tells-scripps-news-i-dont-think-autism-is-genetic

38 replies = new reply since forum marked as read
Highlight: NoneDon't highlight anything 5 newestHighlight 5 most recent replies
FDA Commissioner Dr. Marty Makary tells Scripps News 'I don't think autism is genetic' (Original Post) BumRushDaShow 18 hrs ago OP
leucovorin-I have no doubt that some Republicans are making a ton of money off this stuff Walleye 17 hrs ago #1
You didn't see them generations ago bc they were warehoused in insane asylums. . . . nt Bernardo de La Paz 17 hrs ago #2
Exactly. Timeflyer 15 hrs ago #6
Or the family attic Hekate 6 hrs ago #29
Or died. RedArkGuy 1 hr ago #38
it wasn't REPORTED as much generations ago Skittles 17 hrs ago #3
Yes and just lived out their lives "Hermits" and 'Non-social" or "Anti-social" or "Non-conformists" LiberalArkie 16 hrs ago #5
wow, another post worth of its own thread Skittles 8 hrs ago #22
Something I did not figure out until about a year ago, A lot of us can not say NO. LiberalArkie 7 hrs ago #24
had never thought of that Skittles 6 hrs ago #26
You must tell him as most guys do not know or realize it. I wondered most of my life why I could not keep anything LiberalArkie 5 hrs ago #30
alas my brother passed in 2021 Skittles 5 hrs ago #33
Why? Cirsium 6 hrs ago #28
For personal reasons............... Lovie777 16 hrs ago #4
same Skittles 7 hrs ago #23
What?! yardwork 14 hrs ago #7
Apparently he has never heard of science or history. mwmisses4289 14 hrs ago #8
Good Lord. yardwork 14 hrs ago #9
It's not in their "world" (that they are willing to admit to) BumRushDaShow 14 hrs ago #10
Dr. Malarky Marthe48 14 hrs ago #11
There is definitely a strong genetic component. High-functioning autism runs in our family across 4 generations Martin68 14 hrs ago #12
It's definitely a continuum. yardwork 13 hrs ago #16
"I don't believe" PSPS 14 hrs ago #13
Quack, Quack, Quack, Quack, Quack, Quack, BootinUp 14 hrs ago #14
Quack back at ya. twodogsbarking 13 hrs ago #15
The modern-day phenomenon liberalgunwilltravel 12 hrs ago #17
I think there is a genetic component NH Ethylene 12 hrs ago #18
Autism is not new. ananda 12 hrs ago #19
But recognition and diagnosis have changed drastically over the years. eppur_se_muova 5 hrs ago #31
I don't exactly consider autism a defect. ananda 5 hrs ago #32
Call it a 'condition', then. Whatever you call it, it is something which only slowly came to be recognized. eppur_se_muova 5 hrs ago #34
Of course it exists. ananda 5 hrs ago #35
This message was self-deleted by its author valleyrogue 2 hrs ago #37
What I don't understand is why a high functioning and low functioning autism are both autism womanofthehills 3 hrs ago #36
He is shockingly uninformed. Tanuki 10 hrs ago #20
I would have been 14. I remember that article vividly. 3catwoman3 8 hrs ago #21
I don't think he knows what he's talking about struggle4progress 7 hrs ago #25
Rosemary Kennedy was given a frontal chelsea0011 6 hrs ago #27

Skittles

(167,701 posts)
3. it wasn't REPORTED as much generations ago
Sat Sep 27, 2025, 06:35 AM
17 hrs ago

long ago many autistic folk were probably put in sanatoriums

why do these fucking morons keep lying about autism? WTF

LiberalArkie

(18,982 posts)
5. Yes and just lived out their lives "Hermits" and 'Non-social" or "Anti-social" or "Non-conformists"
Sat Sep 27, 2025, 07:20 AM
16 hrs ago

A lot of words for people like me. Now that I know what I am, I can look at my family tree and spot guys like myself back in the 1000's.

Even all the western and cowboy shows always had characters who were just the blacksmith who was single, lived alone, just did the job, went home, ate slept and went back to the work location. No parties, no socializing just solitude and maybe a hobby. Just the people who kept things working and the ones who were always made fun of.


The reason they believe it is something new is because of the Internet. We can now find other people like ourselves. we can now figure out
"OMG, THAT IS WHY I AM LIKE I AM". and that folks is an amazing thing to find out when you are in your 60's. Now 77 and that was the best thing I ever found out.

Skittles

(167,701 posts)
22. wow, another post worth of its own thread
Sat Sep 27, 2025, 03:44 PM
8 hrs ago

yes, as the sister of a severely autistic younger brother it is heartbreaking to realize how such folk were treated in the past and so disgusting to see what is going on now - what Trump and RFJ Jr are doing is pretty much the GOP playbook now - find a target and demonize them.......they've done it to POC, immigrants, LGBTQ, and now anyone on the Spectrum........seems to me like none of those folk are the issue, MAGA assholes are the real problem

LiberalArkie

(18,982 posts)
24. Something I did not figure out until about a year ago, A lot of us can not say NO.
Sat Sep 27, 2025, 04:14 PM
7 hrs ago

Someone asks "Can I use your car?" Yea sir

"Can I borrow $500?" Oh. all I have is $450, but here ya go.

The big one... Neighbor asks me to leave my house to him in my will. I told him that I do not have a will as I do not have anything worth anything but my little house and the banks would put a lean on it for credit card debt anyway.
Well you can just let us have it and we will take care of it..
Never thought that my neighbor would charge me rent on something that cost them nothing..

Yea, if he is inclined to be a friendly and giving person, this is a very big deal..

In my 20's a guy at work asked me to co-sign a note for a new 69 Corvette.. Yep, skipped out

I hope kids these days are taught that us on the spectrum are VERY EASY marks. People do not have to work very hard even to con us.

Skittles

(167,701 posts)
26. had never thought of that
Sat Sep 27, 2025, 04:53 PM
6 hrs ago

yes I can see how that could happen, for sure

my brother received benefits from my dad's military service and I can easily see some families trying to take advantage of that

LiberalArkie

(18,982 posts)
30. You must tell him as most guys do not know or realize it. I wondered most of my life why I could not keep anything
Sat Sep 27, 2025, 06:02 PM
5 hrs ago

I had had decent paying jobs, but kept giving it away. I think it stems from wanting to have friends and only attracting narcissistic people. Those seem to see us coming from a mile away.

I remember working in NYC and going out with co workers every few nights and end up paying for all the drinks. Always..

Now I know about it and I still almost give in, but I reach for my phone in my pocket like I have a call and their moment is gone. A side note is now that I have told a couple of people is that they never ask me for anything at all, ever.

Good luck

Skittles

(167,701 posts)
33. alas my brother passed in 2021
Sat Sep 27, 2025, 06:15 PM
5 hrs ago

Last edited Sat Sep 27, 2025, 07:25 PM - Edit history (1)

he was in hospice and due to Covid I could not visit him - I was out of state and skyped with him via a nurse but he looked confused, like he didn't recognize me

I feel sad when I think of his life - autistic folk notoriously don't like change but that's all we had growing up in a military family - we moved constantly, sometimes overseas.....different schools almost yearly.

Now when so much more is known about autism there should be great advances in how such children are educated, for example......but now we have a bunch of quacks using these folk as political targets.....it is deeply disturbing.

Cirsium

(2,901 posts)
28. Why?
Sat Sep 27, 2025, 05:17 PM
6 hrs ago

I think they are targeting people deemed unworthy, similarity to what was done in Germany during the early stages of the Nazi regime. "Lebensunwertes Leben." It is the predictable next step in the catastrophic course down which we are being driven.

In a time when the voices of neurodivergent individuals are only beginning to be heard and valued on their own terms, it is deeply disturbing to witness public figures—especially those seeking high office—revive narratives that dehumanise and diminish them. Recent comments by Secretary Robert F. Kennedy Jr., suggesting that autistic individuals are a “burden” on society due to their inability to “work” or “pay taxes,” warrant not just outrage—but reflection. These are not merely careless remarks; they are emblematic of a deeper, more insidious problem: the resurgence of a logic that history has already exposed as deadly.

To understand the gravity of such rhetoric, we must revisit one of the most chilling ideological and bureaucratic programmes of the 20th century: Aktion T4 in Nazi Germany. Between 1939 and 1945, this state-sanctioned “euthanasia” programme targeted individuals deemed “Lebensunwertes Leben”—“life unworthy of life.” The victims were not soldiers, criminals, or political opponents; they were disabled children, neurodivergent individuals, people with mental illness or intellectual disabilities—those who, in the regime’s cold estimation, failed to meet a standard of economic or biological “fitness.”

Before the gas chambers of Auschwitz and Sobibor, before the industrialised murder of millions, came the sterilisation clinics and “mercy killings” in German hospitals. These early atrocities were justified not on the grounds of hatred or vengeance, but on economics. The Nazi regime framed the existence of disabled and neurodivergent people as a financial burden on the state. In internal documents and propaganda, their continued care was described as wasteful, inefficient, and unfair to the productive majority. The German term Ausmerzen, meaning “to eradicate,” was used to describe this policy of quiet, systematic elimination.

The machinery of death began not with bullets or gas—but with ideas. With speeches. With normalised conversations about who “contributes” to society, and who does not. And now, nearly a century later, we are hearing faint but unmistakable echoes of that same logic.

https://publichealthpolicyjournal.com/life-unworthy-of-life-historical-amnesia-ausmerzen-and-the-rhetoric-surrounding-autism/

Skittles

(167,701 posts)
23. same
Sat Sep 27, 2025, 03:48 PM
7 hrs ago

I had a severely autistic younger brother and also I remember a great-uncle who was a lot like him - of course, back then he was pegged as "brain damaged" (my younger brother was labeled "emotionally disturbed)" - but even as a kid I knew Uncle Henry was in many ways smarter than the people around him - and my younger brother, he had savant tendencies with certain subjects, like sports.....he read extensively and knew a lot.

yardwork

(68,141 posts)
7. What?!
Sat Sep 27, 2025, 09:03 AM
14 hrs ago

The head of the FDA doesn't know that there are nonverbal people with autism in their 60s and 70s?

He's never heard of group homes?

BumRushDaShow

(160,708 posts)
10. It's not in their "world" (that they are willing to admit to)
Sat Sep 27, 2025, 09:22 AM
14 hrs ago

I remember back in the late '60s, such a facility was opened near where I grew up called "Northwest Center". During the '80s, when many of the "institutions" had closed or were being phased out, they expanded exponentially in the Philly metro area. Now they have locations across the state and looking it up, they were apparently bought in 2018 and now go by the name "Merakey", a non-profit entity that provides developmental and mental health services for adults. I expect they even offer rehabilitative services for individuals to be able to operate in the workplace (the federal government has hired employees from places like that to do custodial and other services work).

Martin68

(26,517 posts)
12. There is definitely a strong genetic component. High-functioning autism runs in our family across 4 generations
Sat Sep 27, 2025, 09:40 AM
14 hrs ago

that I know of. Farther back it is difficult to discern.

yardwork

(68,141 posts)
16. It's definitely a continuum.
Sat Sep 27, 2025, 09:57 AM
13 hrs ago

We now call a lot of things "autism" that were described in different ways over the ages. I see it all over my family tree, too.

I think a lot of "geniuses" who invented and created things were on the autism spectrum.

PSPS

(14,955 posts)
13. "I don't believe"
Sat Sep 27, 2025, 09:40 AM
14 hrs ago

Another quack on bob's payroll who has his own "beliefs" like some people "believe" the earth is flat. Forget science, go on your "gut feeling" (and whatever gets more sales for your wacky books!!111!!)

BootinUp

(50,466 posts)
14. Quack, Quack, Quack, Quack, Quack, Quack,
Sat Sep 27, 2025, 09:43 AM
14 hrs ago

Quack, Quack, Quack, Quack, Quack, Quack,
Quack, Quack, Quack, Quack, Quack, Quack,
Quack, Quack, Quack, Quack, Quack, Quack,
Quack, Quack, Quack, Quack, Quack, Quack …

17. The modern-day phenomenon
Sat Sep 27, 2025, 11:24 AM
12 hrs ago

Is a bunch of quacks pushing junk science and lies. Everyone of them should lose their medical license, if they even have one. And they should all be charged with reckless endangerment.

NH Ethylene

(31,216 posts)
18. I think there is a genetic component
Sat Sep 27, 2025, 11:34 AM
12 hrs ago

We are as close minded as RFK if we don't consider all angles on autism. There seems to be a genetic component, but there are a number of environmental insults to the nervous system in our modern world that could conceivably account for the high incidence of autism (and yes, it's high, even considering how many kids are diagnosed with mild forms who would not have been in past decades). So many, in fact, it would be hard to pin down causative factors because there are just so many, particularly exposures during pregnancy, toxins such as pesticides, air pollution, heavy metal exposure, etc. Also the older ages of new mothers. Vaccines containing ethylmercury were a good candidate for study, back in the day, but of course studies ruled them out plus they were phased out in 2001.

RFK's anti-vaccine stance is ridiculous and dangerous, but genetic vs environmental causes of autism are not football teams where you back one or the other. A curious and open mind is needed to get to the root cause (or more likely, causes) of such a prevalent disorder.

eppur_se_muova

(40,108 posts)
31. But recognition and diagnosis have changed drastically over the years.
Sat Sep 27, 2025, 06:10 PM
5 hrs ago

Autism as a medical term was only introduced in 1911. And the recognition that there is a 'spectrum' of related conditions is much more recent.

It's a classic case of "there weren't as many cases reported in the past because they weren't recognized in the past". True of many phenomena, and not just in medicine.

The number of people who died of COVID-19 initially was heavily under-reported because not every case was autopsied, so an ultimate (as opposed to proximate) Cause of Death was not established. It wasn't worth the risk of exposure to a highly contagious and fairly lethal disease for the Medical Examiners to be examining the bodies of people who obviously had COVID, but it meant they couldn't sign off on COVID as the established cause.

Deaths due to heatstroke are largely under-reported because the forensic evidence for heatstroke is far from unique, and hard to distinguish from other causes. The living patient may have suffered from heatstroke in an obvious way and under obvious circumstances as confirmed by multiple witnesses, but chances are that won't be reported as the COD, particularly if the patient was already in ill health otherwise.

This is such a well-established, known defect in the study of diseases that no "expert" has any right to be unaware of it -- but RFKJ appointed him anyway.

eppur_se_muova

(40,108 posts)
34. Call it a 'condition', then. Whatever you call it, it is something which only slowly came to be recognized.
Sat Sep 27, 2025, 06:18 PM
5 hrs ago

We still don't understand it very well at all, but denying that it exists, or promoting quack conspiracy theories re. its cause(s) is no longer even remotely consistent with what few facts ARE known.

ananda

(33,315 posts)
35. Of course it exists.
Sat Sep 27, 2025, 06:21 PM
5 hrs ago

And, I know for a fact, that neuro-divergent
people are wonderful and have a lot to offer
all of us.

Response to eppur_se_muova (Reply #34)

womanofthehills

(10,404 posts)
36. What I don't understand is why a high functioning and low functioning autism are both autism
Sat Sep 27, 2025, 08:32 PM
3 hrs ago

My significant other who is very bright, college educated has an autism diagnosis -

But so does a friend’s child who can’t speak, swirls around, bangs his head, is not bathroom trained and will never have a job or live independently. I think instead of one long spectrum- it should be divided.

We know that pesticides, heavy metals, toxic chemicals could be involved. When saying it’s genetic - a second possibility could be lots of people in same family exposed to same toxins -

Example - Navajo SW families all living in a house built with radioactive soil, entire farm families exposed to pesticides, even a non farm family where someone is always setting pesticide bombs in their house. So many toxins in the world - just living near a factory. In NM, rows of houses around Intel are vacant because of toxic fumes being released.

Nothing is black and white.

Tanuki

(16,086 posts)
20. He is shockingly uninformed.
Sat Sep 27, 2025, 01:28 PM
10 hrs ago

The behaviors he says were unheard of a generation ago were common knowledge not only in the medical and mental health communities but to anyone who read Life magazine 60 years ago:

https://publications.aap.org/pediatrics/article-abstract/133/3/364/32244/Screams-Slaps-and-Love-The-Strange-Birth-of?redirectedFrom=fulltext

"On May 7, 1965, an extraordinary photo essay titled “Screams, Slaps, and Love” appeared in the pages of Life magazine. It portrayed the lives of 4 “utterly withdrawn children whose minds are sealed against all human contact and whose uncontrolled madness had turned their homes into hells.”1 Their diagnosis was “childhood schizophrenia,” the term applied at the time to the condition we know as autism. Two were nonverbal, 2 others had no language other than endlessly repeating television commercial jingles, and all 4 exhibited very disruptive behaviors such as head-banging to the point of bruising.

The article’s focus was on a novel treatment that had recently been developed for autism at the University of California at Los Angeles (UCLA). In an age when psychoanalytic ideas dominated therapy for autism in the United States, this new intervention was grounded in behaviorism.2 The therapists in the photo essay were depicted..."

struggle4progress

(124,634 posts)
25. I don't think he knows what he's talking about
Sat Sep 27, 2025, 04:33 PM
7 hrs ago

Do we ask the autism experts for their views on surgical oncology? No? Then maybe we shouldn't ask surgical oncologists for their views on autism

chelsea0011

(10,174 posts)
27. Rosemary Kennedy was given a frontal
Sat Sep 27, 2025, 05:07 PM
6 hrs ago

lobectomy because of her mood swings. It’s not known if she was autistic or on the spectrum or some other form of illness or not. That was a thing in the 50’s and 60’s. That would be RFK Jr’s aunt.

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