Ultra-processed food linked to harm in every major human organ, study finds
World’s largest scientific review warns consumption of UPFs poses seismic threat to global health and wellbeing

Andrew Gregory Health editor
Tue 18 Nov 2025 18.30 EST


Ultra-processed food (UPF) is linked to harm in every major organ system of the human body and poses a seismic threat to global health, according to the world’s largest review.

UPF is also rapidly displacing fresh food in the diets of children and adults on every continent, and is associated with an increased risk of a dozen health conditions, including obesity, type 2 diabetes, heart disease and depression.

The sharp rise in UPF intake worldwide is being spurred by profit-driven corporations using a range of aggressive tactics to drive consumption, skewer scientific debate and prevent regulation, the review of evidence suggests.

The findings, from a series of three papers published in the Lancet, come as millions of people increasingly consume UPF such as ready meals, cereals, protein bars, fizzy drinks and fast food.

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